The United States and Canada have a reciprocity agreement, which recognizes a Canadian-issued commercial driver's licence as proof of medical fitness. However, in the United States, the operator of a Class 5 vehicle must have a commercial medical, if the vehicle or vehicle combination weighs or has a rated capacity (Gross Vehicle Weight Rating) over 4,536 kg.

The United States commercial medical requirements also apply to farm-use vehicles registered in Class F, but do not apply to private-use vehicles (e.g., when vacationing in the United States towing a recreational vehicle).

For more information please refer to the Saskatchewan Professional Driver's Handbook.